Off-spinner Nathan Lyon finished with 4-78 as Pakistan are bowled out for 282 on opening day
Australia, in reply to Pakistan's 282 all out, were 20-2 at close on the first day of the second Test in Abu Dhabi on Tuesday.
Aaron Finch was unbeaten on 13 while nightwatchman Peter Siddle was dismissed off the last ball of the day for four.
Debutant opener Fakhar Zaman and skipper Safraz Ahmed each scored 94 after Pakistan won the toss and opted to bat at Sheikh Zayed Stadium.
Off-spinner Nathan Lyon finished with 4-78 and leg-spinner Marnus Labuschagne took 3-45. The first Test ended in a draw in Dubai last week.