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Sun 1 Oct 2006 12:00 AM

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SSRI effective on premature ejaculation

The first tailor-made medication for premature ejaculation has been found to be safe and effective, a new study reports.

The drug dapoxetine lengthened the duration of intercourse by three to four times in an American study of 2,600 men, The Lancet reported.

University of Minnesota researchers found taking the drug increased the average duration of sex from less than a minute to three minutes 19 seconds.

Premature ejaculation affects up to a third of men, but there is no medication indicated for the condition on the market.

Current treatments typically involve counselling and the use of selective serotonin reuptake inhibitors (SSRIs); although these are not specifically licensed for premature ejaculation.

While dapoxetine is an SSRI, it has been specifically tailored for premature ejaculation.

It can be used on-demand rather than needing to be taken over the long-term.

More than 2,600 men with moderate to severe ejaculation problems were included in the trial either received a placebo, 30mg of dapoxetine or 60mg of dapoxetine.

On average, at the start of the study, the men ejaculated less than a minute after penetration.

After 12 weeks, that time extended to an average of one minute 45 seconds for those on the placebo, two minutes 47 seconds for those on 30mg dapoxetine, and three minutes 19 seconds for those on 60mg.

Dr Jon Pryor, who headed the trial, said:

“Dapoxetine improved patients’ perceptions of control over ejaculation, satisfaction with sexual intercourse, and overall impression of change in condition.

“Partners benefited through improved satisfaction with sexual intercourse.”

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