Defending champion Kirani James of Grenada took silver in 43.76sec, with American Lashawn Merritt bronze (43.85).
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Van Niekerk, running in the unfavoured lane eight, blasted off the final corner to time 43.03 sec, 0.15sec quicker than Michael Johnson’s previous world best set in Seville in 1999.
Defending champion Kirani James of Grenada took silver in 43.76sec, with American Lashawn Merritt bronze (43.85).
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